|
KMID : 0043320120350040639
|
|
Archives of Pharmacal Research
2012 Volume.35 No. 4 p.639 ~ p.645
|
|
|
Improved synthesis of a DNA-dependent protein kinase inhibitor IC86621
|
|
Chandra Girish
Alexander Varughese
Lee Hyuk-Woo
Jeong Lak-Shin
|
|
|
Abstract
|
|
|
|
An improved synthesis of DNA-dependent protein kinase inhibitor, IC86621 is described. This developed method provides an easy access to this simple molecule by using amination, acetylation and Fries rearrangement reactions.
|
|
|
KEYWORD
|
|
|
DNA-dependent protein kinase (DNA-PK), Buchwald-Hartwig amination, Fries rearrangement
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|